BDBM50333561 2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidine-4-ylamino}-3-fluoro-N-methyl-benzamide::CHEMBL1642135

SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3CCN(CCOC)CCc3c2)ncc1Cl

InChI Key InChIKey=JUTMYSXKSLZJQM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333561   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333561(2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahy...)
Affinity DataIC50:  19nMAssay Description:Inhibition of c-Met expressed in human GTL-16 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333561(2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahy...)
Affinity DataIC50:  8nMAssay Description:Inhibition of c-Met cytoplasmic domain expressed in baculovirus after 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333561(2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahy...)
Affinity DataIC50:  230nMAssay Description:Inhibition of insulin receptor after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed