BDBM50333939 (R)-N-(3-amino-3-oxo-1-phenylpropyl)-5-fluoro-4-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide::CHEMBL1644428

SMILES NC(=O)C[C@@H](NC(=O)c1cc(c(F)s1)-c1ccc(OC(F)(F)F)cc1)c1ccccc1

InChI Key InChIKey=CWBWNBWJSLNHOL-MRXNPFEDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333939   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333939((R)-N-(3-amino-3-oxo-1-phenylpropyl)-5-fluoro-4-(4...)
Affinity DataIC50:  85nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed