BDBM50334049 5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2-dihydroquinolin-3(4H)-one::CHEMBL1644754
SMILES CC1C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12
InChI Key InChIKey=PDCRQOSNBYFZJI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50334049
Affinity DataKi: 5.80nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...More data for this Ligand-Target Pair
Affinity DataEC50: 235nMAssay Description:Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with GRE assessed as transactivation activity by luciferase reporter ...More data for this Ligand-Target Pair