BDBM50334093 2-[5-Chloro-2-(1-isobutyl-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino)-pyrimidin-4-ylamino]-3-fluoro-N-methyl-benzamide::CHEMBL1644814

SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)N(CC(C)C)C(=O)CCC3(C)C)ncc1Cl

InChI Key InChIKey=VZXLODFBDTXBJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334093   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334093(2-[5-Chloro-2-(1-isobutyl-5,5-dimethyl-2-oxo-2,3,4...)
Affinity DataIC50:  84nMAssay Description:Inhibition of c-MetChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334093(2-[5-Chloro-2-(1-isobutyl-5,5-dimethyl-2-oxo-2,3,4...)
Affinity DataIC50:  840nMAssay Description:Inhibition of IR kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334093(2-[5-Chloro-2-(1-isobutyl-5,5-dimethyl-2-oxo-2,3,4...)
Affinity DataIC50:  214nMAssay Description:Inhibition of human c-Met in human GTL16 cells by cell-based assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed