BDBM50334224 CHEMBL1641992::N-(1-(3-Bromophenylamino)-4-cyanoisoquinolin-7-yl)-3-(4-methylpiperazin-1yl)propanamide

SMILES CN1CCN(CCC(=O)Nc2ccc3c(cnc(Nc4cccc(Br)c4)c3c2)C#N)CC1

InChI Key InChIKey=NUEIZCVGJKOLIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334224   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50334224(CHEMBL1641992 | N-(1-(3-Bromophenylamino)-4-cyanoi...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50334224(CHEMBL1641992 | N-(1-(3-Bromophenylamino)-4-cyanoi...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of MLCK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed