BDBM50334357 4-(3-(4-(trifluoromethyl)phenyl)ureido)benzenesulfonamide::4-{[([4-(Trifluoromethyl)phenyl]amino}carbonyl)amino]benzenesulfonamide::CHEMBL1337519

SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=PTTQRLLAHZHAEV-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50334357   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334357(4-(3-(4-(trifluoromethyl)phenyl)ureido)benzenesulf...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 12 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334357(4-(3-(4-(trifluoromethyl)phenyl)ureido)benzenesulf...)
Affinity DataKi:  6.20nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 9 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334357(4-(3-(4-(trifluoromethyl)phenyl)ureido)benzenesulf...)
Affinity DataKi:  9.70nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM50334357(4-(3-(4-(trifluoromethyl)phenyl)ureido)benzenesulf...)
Affinity DataKi:  69nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv1284 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM50334357(4-(3-(4-(trifluoromethyl)phenyl)ureido)benzenesulf...)
Affinity DataKi:  533nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv3273 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334357(4-(3-(4-(trifluoromethyl)phenyl)ureido)benzenesulf...)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334357(4-(3-(4-(trifluoromethyl)phenyl)ureido)benzenesulf...)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed