BDBM50334478 4-((3,5-bis(4-(trifluoromethoxy)phenyl)-1H-pyrazol-1-yl)methyl)-N-(2H-tetrazol-5-yl)benzamide::CHEMBL1644180

SMILES FC(F)(F)Oc1ccc(cc1)-c1cc(-c2ccc(OC(F)(F)F)cc2)n(Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)n1

InChI Key InChIKey=JXOWRNXJRPAHHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334478   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334478(4-((3,5-bis(4-(trifluoromethoxy)phenyl)-1H-pyrazol...)
Affinity DataIC50:  43nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334478(4-((3,5-bis(4-(trifluoromethoxy)phenyl)-1H-pyrazol...)
Affinity DataIC50:  47nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed