BDBM50334605 2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyrimidin-2-ylamino)-8-methoxy-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-N,N-dimethylacetamide::CHEMBL1642264

SMILES COc1cc(ccc1Nc1nc(Nc2cc3CCN(CC(=O)N(C)C)CCc3cc2OC)ncc1Cl)C#N

InChI Key InChIKey=CPVCXTGQEFSNOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334605   

TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334605(2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyr...)
Affinity DataIC50:  233nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334605(2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334605(2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyr...)
Affinity DataIC50:  65nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed