BDBM50336147 CHEMBL1669535::cis-(+/-)-4-chloro-N-(2-(hydroxymethyl)cyclohexyl)-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carboxamide

SMILES OC[C@H]1CCCC[C@H]1NC(=O)c1noc(c1Cl)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=SNMGRCYWZKLHMB-DGCLKSJQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336147   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Sharpe And Dohme

Curated by ChEMBL
LigandPNGBDBM50336147(CHEMBL1669535 | cis-(+/-)-4-chloro-N-(2-(hydroxyme...)
Affinity DataIC50:  48nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed