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BDBM50336276 1-oxo-1,3,4,5,6,7,8,9,10,11-decahydrobenzo[c][1]oxacyclotridecine-13,15-diyl diacetate::CHEMBL1669774

SMILES: CC(=O)Oc1cc2CCCCCCCCCOC(=O)c2c(OC(C)=O)c1

InChI Key: InChIKey=WZVXGNPFGYVCOY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336276   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50336276
PNG
(1-oxo-1,3,4,5,6,7,8,9,10,11-decahydrobenzo[c][1]ox...)
Show SMILES CC(=O)Oc1cc2CCCCCCCCCOC(=O)c2c(OC(C)=O)c1
Show InChI InChI=1S/C20H26O6/c1-14(21)25-17-12-16-10-8-6-4-3-5-7-9-11-24-20(23)19(16)18(13-17)26-15(2)22/h12-13H,3-11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.06E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of progesterone receptor ligand binding domain expressed in HEK293T cells


Bioorg Med Chem Lett 21: 1171-5 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.101
BindingDB Entry DOI: 10.7270/Q2X92BKM
More data for this
Ligand-Target Pair
mineralocorticoid


(RAT)
BDBM50336276
PNG
(1-oxo-1,3,4,5,6,7,8,9,10,11-decahydrobenzo[c][1]ox...)
Show SMILES CC(=O)Oc1cc2CCCCCCCCCOC(=O)c2c(OC(C)=O)c1
Show InChI InChI=1S/C20H26O6/c1-14(21)25-17-12-16-10-8-6-4-3-5-7-9-11-24-20(23)19(16)18(13-17)26-15(2)22/h12-13H,3-11H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 820n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...


Bioorg Med Chem Lett 21: 1171-5 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.101
BindingDB Entry DOI: 10.7270/Q2X92BKM
More data for this
Ligand-Target Pair