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BDBM50336282 (R)-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-benzo[c][1]oxacyclododecine-12,14-diyl dipropionate::CHEMBL1669763

SMILES: CCC(=O)Oc1cc2CCCCCCC[C@@H](C)OC(=O)c2c(OC(=O)CC)c1

InChI Key: InChIKey=NXPNFPYSNSBNCP-OAHLLOKOSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336282   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
mineralocorticoid


(RAT)
BDBM50336282
PNG
((R)-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-b...)
Show SMILES CCC(=O)Oc1cc2CCCCCCC[C@@H](C)OC(=O)c2c(OC(=O)CC)c1
Show InChI InChI=1S/C22H30O6/c1-4-19(23)27-17-13-16-12-10-8-6-7-9-11-15(3)26-22(25)21(16)18(14-17)28-20(24)5-2/h13-15H,4-12H2,1-3H3/t15-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.17E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...


Bioorg Med Chem Lett 21: 1171-5 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.101
BindingDB Entry DOI: 10.7270/Q2X92BKM
More data for this
Ligand-Target Pair