BDBM50336820 CHEMBL1672127::[5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-ethyl-4-(4-methylphenyl)pyridin-3-yl]acetic acid hydrate

SMILES CCc1nc(CC(C)(C)C)c(CN)c(-c2ccc(C)cc2)c1CC(O)=O

InChI Key InChIKey=HQVOROHHYWZJLD-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336820   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336820(CHEMBL1672127 | [5-(Aminomethyl)-6-(2,2-dimethylpr...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of DPP4 in human Caco2 cells after 60 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336820(CHEMBL1672127 | [5-(Aminomethyl)-6-(2,2-dimethylpr...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of FLAG-tagged human DPP9 expressed in human 293F cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336820(CHEMBL1672127 | [5-(Aminomethyl)-6-(2,2-dimethylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FLAG-tagged human DPP8 expressed in human 293F cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336820(CHEMBL1672127 | [5-(Aminomethyl)-6-(2,2-dimethylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat kidney DPP2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed