BDBM50336872 CHEMBL1672320::N-(6-(5-aminopyrazin-2-yl)-2-morpholinopyrimidin-4-yl)quinolin-3-amine

SMILES Nc1cnc(cn1)-c1cc(Nc2cnc3ccccc3c2)nc(n1)N1CCOCC1

InChI Key InChIKey=GTSVWFMEUUHFOQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336872   

LigandPNGBDBM50336872(CHEMBL1672320 | N-(6-(5-aminopyrazin-2-yl)-2-morph...)
Affinity DataEC50:  3.30E+3nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser473 in human A2780 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50336872(CHEMBL1672320 | N-(6-(5-aminopyrazin-2-yl)-2-morph...)
Affinity DataIC50:  44nMAssay Description:Inhibition of PI3Kalpha after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed