BDBM50337317 5-(1-(3-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682348

SMILES Clc1cccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)c1

InChI Key InChIKey=WVZWFOGYDXWKPT-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337317   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337317(5-(1-(3-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  23nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337317(5-(1-(3-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  39nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337317(5-(1-(3-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  160nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337317(5-(1-(3-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of JAK2 after 1 hr using biotinylated PDKtide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337317(5-(1-(3-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  1.31E+4nMAssay Description:Inhibition of KDR after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed