BDBM50337320 5-(1-(3-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682351

SMILES Fc1cccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)c1

InChI Key InChIKey=RZLXGZULLYTTFO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50337320   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337320(5-(1-(3-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  26nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337320(5-(1-(3-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  42nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337320(5-(1-(3-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  180nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337320(5-(1-(3-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed