BDBM50337377 CHEMBL1682552::N-cyclohexyl-2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidin-3-amine

SMILES C1CCC(CC1)Nc1c(nc2ncccn12)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=CALAEFSQWBJMDU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337377   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337377(CHEMBL1682552 | N-cyclohexyl-2-(1H-indazol-5-yl)im...)
Affinity DataKi:  10nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337377(CHEMBL1682552 | N-cyclohexyl-2-(1H-indazol-5-yl)im...)
Affinity DataKi:  245nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337377(CHEMBL1682552 | N-cyclohexyl-2-(1H-indazol-5-yl)im...)
Affinity DataKi:  307nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337377(CHEMBL1682552 | N-cyclohexyl-2-(1H-indazol-5-yl)im...)
Affinity DataKi: >1.80E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337377(CHEMBL1682552 | N-cyclohexyl-2-(1H-indazol-5-yl)im...)
Affinity DataKi:  5.33E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed