BDBM50337695 3-(5-(3-bromo-4-(4-methylpiperazin-1-yl)phenyl)-1H-pyrazol-3-yl)-N-(cyanomethyl)benzamide::CHEMBL1683424

SMILES CN1CCN(CC1)c1ccc(cc1Br)-c1cc(n[nH]1)-c1cccc(c1)C(=O)NCC#N

InChI Key InChIKey=AKAFQYZCIMMDMT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337695   

TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337695(3-(5-(3-bromo-4-(4-methylpiperazin-1-yl)phenyl)-1H...)
Affinity DataIC50:  87nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPkd1(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337695(3-(5-(3-bromo-4-(4-methylpiperazin-1-yl)phenyl)-1H...)
Affinity DataEC50:  680nMAssay Description:Inhibition of PKD1 in rat neonatal ventricular myocytes expressing GFP-HDAC5 assessed as inhibition of phosphorylation-dependent HDAC5 nuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed