BDBM50337826 1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)piperidine::CHEMBL1683878::US10562878, Compound 109

SMILES Clc1ccc(cc1Cl)C1(CN2CCCCC2)CCCCC1

InChI Key InChIKey=QQKNLGCYRCQFQP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337826   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337826(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)piperi...)
Affinity DataIC50:  9.67E+3nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337826(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)piperi...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337826(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)piperi...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337826(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)piperi...)
Affinity DataIC50:  9.67E+3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337826(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)piperi...)
Affinity DataIC50:  114nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337826(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)piperi...)
Affinity DataIC50:  114nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed