BDBM50338058 CHEMBL1684656::N1,N1-dimethyl-N2-(3-(6-methyl-1H-indol-2-yl)-1H-indazol-5-yl)propane-1,2-diamine

SMILES CC(CN(C)C)Nc1ccc2[nH]nc(-c3cc4ccc(C)cc4[nH]3)c2c1

InChI Key InChIKey=OZUVLXJPLOJMED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338058   

TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50338058(CHEMBL1684656 | N1,N1-dimethyl-N2-(3-(6-methyl-1H-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant GST-tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed