BDBM50338311 (+/-)-4-((3R,4S)-3-hydroxy-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2,3,4-tetrahydroquinolin-5-yl)but-3-en-2-one::CHEMBL1682430
SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(C=CC(C)=O)c12)-c1cccc2cc[nH]c12
InChI Key InChIKey=AZZFDTTVGWXWEX-UPCLLVRISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50338311
Affinity DataKi: 10.4nMAssay Description:Displacement of radiolabeled dexamethasone from GRMore data for this Ligand-Target Pair
Affinity DataEC50: 112nMAssay Description:Agonist activity at GR expressed in african green monkey CV1 cells transfected with luciferase gene linked to MMTV promoter assessed as induction of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Agonist activity at human GR expressed in NHDF cells assessed as inhibition of IL-6 production by ELISA relative to dexamethasoneMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Agonist activity at GR expressed in IL-1beta- and TNFalpha-stimulated HepG2 cells assessed as inhibition of NFKB- or AP-1 mediated E-selectin transcr...More data for this Ligand-Target Pair