BDBM50338971 CHEMBL1685067::Strobopinin-7-methylether

SMILES COc1cc2OC(CC(=O)c2c(O)c1C)c1ccccc1

InChI Key InChIKey=MJPLGHSVCRZIQU-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338971   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50338971(CHEMBL1685067 | Strobopinin-7-methylether)Copy SMILESCopy InChI

Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

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TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50338971(CHEMBL1685067 | Strobopinin-7-methylether)Copy SMILESCopy InChI

Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of MDR1 expressed in MDCK cells using rhodamine 123 staining by flow cytometryMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50338971(CHEMBL1685067 | Strobopinin-7-methylether)Copy SMILESCopy InChI

Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL