BDBM50339032 5-[(4-(3S)-4-[(1R,2R)-2-methoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]-3-methylpiperazin-1-yl-4-methylpiperidin-1-yl)carbonyl]-4,6-dimethylpyrimidine::CHEMBL1688242

SMILES CO[C@@H]1Cc2cc(ccc2[C@H]1N1CCN(C[C@@H]1C)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C)C(F)(F)F

InChI Key InChIKey=NLPKHHZDESNXNS-GJECAEJISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339032   

TargetC-C chemokine receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339032(5-[(4-(3S)-4-[(1R,2R)-2-methoxy-5-(trifluoromethyl...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at CCR5 in IL-10 stimulated human PBMC cells assessed as MIP-1beta induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339032(5-[(4-(3S)-4-[(1R,2R)-2-methoxy-5-(trifluoromethyl...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 in IL-10-stimulated human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed