BDBM50339212 CHEMBL1689483

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)C(C)(C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)NC1=O)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)NC(C)(C)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(C)=O)C(C)C

InChI Key InChIKey=XZZZULWTZVXHQA-DPXFCLHYSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50339212   

TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to human PlGF-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataKd:  70nMAssay Description:Binding affinity to mouse PlGFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataKd:  9nMAssay Description:Binding affinity to human PlGF-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed