BDBM50339363 (+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxymethylcyclohexylmethoxy)-2-(4-nitrobenzyl)-2,3-dihydroisoindol-1-one::CHEMBL1688268

SMILES OC[C@H]1CC[C@H](COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=KLCITVQDFSSVKO-FKCXMHPPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339363   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339363((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxymethylc...)
Affinity DataIC50:  580nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed