BDBM50339390 (+/-)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cyclopropyl)methoxy)-2-(pyridin-4-ylmethyl)isoindolin-1-one::CHEMBL1688295

SMILES OCC1(COC2(N(Cc3ccncc3)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=XADAKGPPYCKHOU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339390   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL

LigandBDBM50339390((+/-)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cycl...)Copy SMILESCopy InChI

Affinity DataIC50:  2.52E+5nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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