BDBM50339585 4-(2-Hydroxy-ethyl)-phenol::4-(2-hydroxyethyl)phenol::CHEMBL53566::p-Hydroxyphenethyl alcohol::tyrosol

SMILES OCCc1ccc(O)cc1

InChI Key InChIKey=YCCILVSKPBXVIP-UHFFFAOYSA-N

Data  6 KI  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50339585   

TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339585(4-(2-Hydroxy-ethyl)-phenol | 4-(2-hydroxyethyl)phe...)
Affinity DataKi:  850nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339585(4-(2-Hydroxy-ethyl)-phenol | 4-(2-hydroxyethyl)phe...)
Affinity DataKi:  1.08E+3nMAssay Description:Inhibition of Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339585(4-(2-Hydroxy-ethyl)-phenol | 4-(2-hydroxyethyl)phe...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Candida albicans recombinant Nce103 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339585(4-(2-Hydroxy-ethyl)-phenol | 4-(2-hydroxyethyl)phe...)
Affinity DataKi:  8.70E+3nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339585(4-(2-Hydroxy-ethyl)-phenol | 4-(2-hydroxyethyl)phe...)
Affinity DataKi:  1.21E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339585(4-(2-Hydroxy-ethyl)-phenol | 4-(2-hydroxyethyl)phe...)
Affinity DataKi:  4.30E+5nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The State University Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50339585(4-(2-Hydroxy-ethyl)-phenol | 4-(2-hydroxyethyl)phe...)
Affinity DataIC50:  6.68E+3nMAssay Description:Inhibition of SARS-CoV-2 papain-like protease using ISG15-Rh as substrateMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50339585(4-(2-Hydroxy-ethyl)-phenol | 4-(2-hydroxyethyl)phe...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged cytoplasmic c-MET kinase domain (956 to 1390 residues) phosphorylation expressed in baculovirus...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed