BDBM50339765 CHEMBL1689122::rac-2-(4-chloro-2-((2-methyl-4-(phenylsulfonyl)piperazin-1-yl)methyl)phenoxy)acetic acid

SMILES CC1CN(CCN1Cc1cc(Cl)ccc1OCC(O)=O)S(=O)(=O)c1ccccc1

InChI Key InChIKey=KQVTZYFUHDWJOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339765   

TargetProstaglandin D2 receptor 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339765(CHEMBL1689122 | rac-2-(4-chloro-2-((2-methyl-4-(ph...)
Affinity DataIC50:  71nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339765(CHEMBL1689122 | rac-2-(4-chloro-2-((2-methyl-4-(ph...)
Affinity DataIC50:  28nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed