BDBM50339779 CHEMBL1689141::N-{7-[4-(4'-Chloro-biphenyl-2-ylmethyl)piperazin-1-yl]quinazolin-4-yl}-4-((R)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-trifluoromethanesulfonyl-benzenesulfonamide
SMILES CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)Nc1ncnc2cc(ccc12)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1
InChI Key InChIKey=HXYGJHGNMRUJCS-UUWRZZSWSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50339779
TargetBcl-2-like protein 2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of wild type mBimBH3 from Mcl-1 by solution competition assayMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair