BDBM50340431 (4-(1H-imidazol-4-yl)piperidin-1-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone::CHEMBL1761844

SMILES O=C(N1CCC(CC1)c1cnc[nH]1)N1CCCc2ccccc12

InChI Key InChIKey=UTSIHHDNMUZNMG-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340431   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340431((4-(1H-imidazol-4-yl)piperidin-1-yl)(3,4-dihydroqu...)
Affinity DataIC50:  325nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340431((4-(1H-imidazol-4-yl)piperidin-1-yl)(3,4-dihydroqu...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340431((4-(1H-imidazol-4-yl)piperidin-1-yl)(3,4-dihydroqu...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed