BDBM50340458 CHEMBL1762009::Cis-(3S,5R)-N-((R)-1-(4-(tert-butylcarbamoyl)-4-cyclohexylpiperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-3,5-dimethylpiperazine-1-carboxamide
SMILES C[C@H]1CN(C[C@@H](C)N1)C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(CC1)(C1CCCCC1)C(=O)NC(C)(C)C
InChI Key InChIKey=SZGSXARYIZZWDD-QSEAXJEQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50340458
Affinity DataIC50: 33nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair