BDBM50340662 5,7-difluoro-2,2-dimethyl-6-(3-methyl-1H-indol-7-yl)-2,3-dihydroquinolin-4(1H)-one O-1-hydroxy-2-methylpropan-2-yl oxime::CHEMBL1762209
SMILES Cc1c[nH]c2c(cccc12)-c1c(F)cc2NC(C)(C)C\C(=N/OC(C)(C)CO)c2c1F
InChI Key InChIKey=SGSLRJUNARVKFS-RDRPBHBLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50340662
Affinity DataKi: 0.800nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 950nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Binding affinity to mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with PEPCK assessed as GRE activation by luciferase reporter gene ass...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Transrepression activity at glucocorticoid receptor in human NHDF cells assessed as inhibition of IL-1beta-stimulated AP1 dependent IL-6 repression b...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Transrepression activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of TNFalpha/IL1beta-stimulated NFkappaB-dependent E-s...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with GRE assessed as GRE activation by luciferase reporter gene assayMore data for this Ligand-Target Pair