BDBM50340857 CHEMBL1761615::N-(2-(5-chloro-1H-indole-2-carboxamido)phenyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide
SMILES: CN1CCc2nc(sc2C1)C(=O)Nc1ccccc1NC(=O)c1cc2cc(Cl)ccc2[nH]1
InChI Key: InChIKey=HLZHKMHNSZRIOD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Coagulation factor X (Homo sapiens (Human)) | BDBM50340857![]() (CHEMBL1761615 | N-(2-(5-chloro-1H-indole-2-carboxa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human factor 10a using S2222 chromogenic substrate by spectrophotometric analysis | Bioorg Med Chem Lett 21: 2133-40 (2011) Article DOI: 10.1016/j.bmcl.2011.01.132 BindingDB Entry DOI: 10.7270/Q2MK6D60 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |