BDBM50341352 CHEMBL1766580::trans-6-(2,4-Difluorophenoxy)-2-(trans-4-hydroxy-cyclohexylamino)-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

SMILES Cn1c2nc(N[C@H]3CC[C@H](O)CC3)ncc2cc(Oc2ccc(F)cc2F)c1=O

InChI Key InChIKey=QXBFECQVSFWIBC-HDJSIYSDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341352   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50341352(CHEMBL1766580 | trans-6-(2,4-Difluorophenoxy)-2-(t...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed