BDBM50341372 6-(2,4-Difluorophenoxy)-2-isopropylamino-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one::6-(2,4-difluorophenoxy)-8-methyl-2-[(1-methylethyl)amino]pyrido[2,3-d]pyrimidin-7(8H)-one::CHEMBL1232772
SMILES CC(C)Nc1ncc2cc(Oc3ccc(F)cc3F)c(=O)n(C)c2n1
InChI Key InChIKey=HAVJVJFXQRMACG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50341372
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair