BDBM50341769 2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid[6-(4-Cyclopropanecarbonylpiperazin-1-yl)pyridin-3-yl]-amide::CHEMBL1766886

SMILES FC(F)(F)c1oc(nc1C(=O)Nc1ccc(nc1)N1CCN(CC1)C(=O)C1CC1)-c1ccccc1

InChI Key InChIKey=XNPROQNSSCAJLO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341769   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341769(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341769(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  138nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed