BDBM50341796 (1S,2R,3R)-1-[(R)-4-(5-Methoxymethylisoxazol-3-yl)-3-methylpiperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766918

SMILES COCc1cc(no1)N1CCN(C[C@H]1C)S(=O)(=O)N[C@]1([C@H](C)[C@@H]1c1ccccc1)C(O)=O

InChI Key InChIKey=IUIQYGWNHACUOZ-HLBGSYOWSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341796   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341796((1S,2R,3R)-1-[(R)-4-(5-Methoxymethylisoxazol-3-yl)...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341796((1S,2R,3R)-1-[(R)-4-(5-Methoxymethylisoxazol-3-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant TACE after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341796((1S,2R,3R)-1-[(R)-4-(5-Methoxymethylisoxazol-3-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341796((1S,2R,3R)-1-[(R)-4-(5-Methoxymethylisoxazol-3-yl)...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed