BDBM50341799 (1S,2R,3R)-1-(8-Chloro-1,2,3,4-tetrahydropyrido[3',4':4,5]imidazo[1,2-a]pyridine-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766921

SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(C1)nc1cc(Cl)ccn21)C(O)=O

InChI Key InChIKey=OTCWHHBFFQOWCU-DYHNYNMBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341799   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341799((1S,2R,3R)-1-(8-Chloro-1,2,3,4-tetrahydropyrido[3'...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341799((1S,2R,3R)-1-(8-Chloro-1,2,3,4-tetrahydropyrido[3'...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant TACE after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341799((1S,2R,3R)-1-(8-Chloro-1,2,3,4-tetrahydropyrido[3'...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341799((1S,2R,3R)-1-(8-Chloro-1,2,3,4-tetrahydropyrido[3'...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed