BDBM50341860 8-chloro-2-(4-(4-(4-fluorophenyl)-5,6-dihydropyridin-1(2H)-yl)butyl)quinazolin-4(3H)-one::CHEMBL1767068

SMILES Fc1ccc(cc1)C1=CCN(CCCCc2nc3c(Cl)cccc3c(=O)[nH]2)CC1

InChI Key InChIKey=IBIQKJHXTSLLBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341860   

TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50341860(8-chloro-2-(4-(4-(4-fluorophenyl)-5,6-dihydropyrid...)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50341860(8-chloro-2-(4-(4-(4-fluorophenyl)-5,6-dihydropyrid...)
Affinity DataIC50:  13nMAssay Description:Inhibition of full length human PARP-1 after 10 mins by FlashPlate scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed