BDBM50342466 (S)-(4-fluorophenyl)(3-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone::CHEMBL1771653

SMILES Fc1ccc(cc1)C(=O)N1CCC[C@@H](C1)c1nc(no1)-c1cccs1

InChI Key InChIKey=BDWLILFPLXVQLM-ZDUSSCGKSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342466   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50342466((S)-(4-fluorophenyl)(3-(3-(thiophen-2-yl)-1,2,4-ox...)
Affinity DataEC50:  170nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293A cells assessed as increase in glutamate induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed