BDBM50343191 CHEMBL1773578::N-(6-(2-(2-Fluoro-N-methylphenylsulfonamido)pyrimidin-4-yl)benzo-[d]thiazol-2-yl)acetamide

SMILES CN(c1nccc(n1)-c1ccc2nc(NC(C)=O)sc2c1)S(=O)(=O)c1ccccc1F

InChI Key InChIKey=POTXEIKHPXLNLL-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343191   

LigandPNGBDBM50343191(CHEMBL1773578 | N-(6-(2-(2-Fluoro-N-methylphenylsu...)
Affinity DataKi:  65nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50343191(CHEMBL1773578 | N-(6-(2-(2-Fluoro-N-methylphenylsu...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of mTOR assessed as inhibition of 4EBP1 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50343191(CHEMBL1773578 | N-(6-(2-(2-Fluoro-N-methylphenylsu...)
Affinity DataIC50:  676nMAssay Description:Inhibition of AKT phosphorylation at S473 in human U-87MG cells at 5 mM after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed