BDBM50343192 CHEMBL1773579::N-(6-(2-(3-Fluorophenylsulfonamido)pyrimidin-4-yl)benzo-[d]thiazol-2-yl)acetamide

SMILES CC(=O)Nc1nc2ccc(cc2s1)-c1ccnc(NS(=O)(=O)c2cccc(F)c2)n1

InChI Key InChIKey=RVCQQGFXZRUZEZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343192   

LigandPNGBDBM50343192(CHEMBL1773579 | N-(6-(2-(3-Fluorophenylsulfonamido...)
Affinity DataKi:  84nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50343192(CHEMBL1773579 | N-(6-(2-(3-Fluorophenylsulfonamido...)
Affinity DataIC50:  47nMAssay Description:Inhibition of mTOR assessed as inhibition of 4EBP1 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50343192(CHEMBL1773579 | N-(6-(2-(3-Fluorophenylsulfonamido...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of AKT phosphorylation at S473 in human U-87MG cells at 5 mM after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed