BDBM50343998 (2S,3R,4R)-3,4-dihydroxy-2,4-dimethyl-3,4-dihydro-2H-pyrimido[2,1-a]isoquinolin-1-ium-2-carboxylate::CHEMBL1779953::CHEMBL1779954

SMILES CC1(O)C(O)C(C)(N[c+]2n1ccc1ccccc21)C([O-])=O

InChI Key InChIKey=LNMASGINKJPCND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343998   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Joseph Fourier-Grenoble 1/Cnrs

Curated by ChEMBL
LigandPNGBDBM50343998((2S,3R,4R)-3,4-dihydroxy-2,4-dimethyl-3,4-dihydro-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Joseph Fourier-Grenoble 1/Cnrs

Curated by ChEMBL
LigandPNGBDBM50343998((2S,3R,4R)-3,4-dihydroxy-2,4-dimethyl-3,4-dihydro-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed