BDBM50344104 2-(5,5-dimethyl-3-oxo-1-tosylpiperazin-2-yl)-N-((R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)acetamide::CHEMBL1777962

SMILES Cc1ccc(cc1)S(=O)(=O)N1CC(C)(C)NC(=O)C1CC(=O)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12

InChI Key InChIKey=IWSJXYFILWNIQO-QXPUDEPPSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344104   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50344104(2-(5,5-dimethyl-3-oxo-1-tosylpiperazin-2-yl)-N-((R...)
Affinity DataKi:  17.6nMAssay Description:Antagonist activity at human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50344104(2-(5,5-dimethyl-3-oxo-1-tosylpiperazin-2-yl)-N-((R...)
Affinity DataIC50:  136nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium efflux by aquerin based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed