BDBM50344234 CHEMBL1778867::N-((6-(4-fluoro-2-methoxyphenyl)pyrazin-2-yl)methyl)cyclopentanamine

SMILES COc1cc(F)ccc1-c1cncc(CNC2CCCC2)n1

InChI Key InChIKey=NUNBCOKRRSELLT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344234   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344234(CHEMBL1778867 | N-((6-(4-fluoro-2-methoxyphenyl)py...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344234(CHEMBL1778867 | N-((6-(4-fluoro-2-methoxyphenyl)py...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells electrophysiology studyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed