BDBM50344538 CHEMBL1778397::N-methyl-4-(2-(4-(trifluoromethoxy)phenylamino)benzo[d]oxazol-5-yloxy)picolinamide

SMILES CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(OC(F)(F)F)cc4)nc3c2)ccn1

InChI Key InChIKey=ZNYMPMILEBRLNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344538   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344538(CHEMBL1778397 | N-methyl-4-(2-(4-(trifluoromethoxy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed