BDBM50345245 CHEMBL1782516::trans-5-(6-(4-(aminomethyl)cyclohexylamino)pyrazin-2-yl)benzofuran-2-carboxylic acid

SMILES NC[C@H]1CC[C@@H](CC1)Nc1cncc(n1)-c1ccc2oc(cc2c1)C(O)=O

InChI Key InChIKey=GQGBNSOWWUUWLC-NNUKFRKNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345245   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345245(CHEMBL1782516 | trans-5-(6-(4-(aminomethyl)cyclohe...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human Pim2 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 90 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345245(CHEMBL1782516 | trans-5-(6-(4-(aminomethyl)cyclohe...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed