BDBM50345372 (2S,3R,4R,5S,6R)-2-(2-(Allyloxymethyl)-4-chloro-5-((5-(furan-3-yl)thiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1784424

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2ncc(s2)-c2ccoc2)c(Cl)cc1COCC=C

InChI Key InChIKey=RWGWXKKFPBIKSP-MWFZDGHISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345372   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345372((2S,3R,4R,5S,6R)-2-(2-(Allyloxymethyl)-4-chloro-5-...)
Affinity DataIC50:  38.7nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed