BDBM50345572 3-(2-(pyridin-2-yl)ethynyl)-5-fluorobenzonitrile::CHEMBL1784618
SMILES Fc1cc(cc(c1)C#Cc1ccccn1)C#N
InChI Key InChIKey=MEZOEZSKPXUIJA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50345572
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK-293 cells assessed as inhibition of glutamate-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair