BDBM50346020 (2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide::(R)-3-cyclopentyl-2-(4-(methylsulfonyl)phenyl)-N-(thiazol-2-yl)propanamide::CHEMBL1096435::Ro-0281675

SMILES CS(=O)(=O)c1ccc(cc1)[C@@H](CC1CCCC1)C(=O)Nc1nccs1

InChI Key InChIKey=NEQSWPCDHDQINX-MRXNPFEDSA-N

Data  1 Kd  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50346020   

TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50346020((2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-t...)
Affinity DataKd:  500nMAssay Description:Binding affinity to recombinant wild-type human pancreatic glucokinase expressed in Escherichia coli K-12 by isothermal titration calorimetry in pres...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50346020((2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-t...)
Affinity DataEC50:  500nMAssay Description:Activation of glucokinase (unknown origin)More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50346020((2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-t...)
Affinity DataEC50:  690nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair