BDBM50346153 5-(4-methoxy-2-(2-(piperidin-1-yl)ethoxy)phenyl)-3-phenylisoxazole::CHEMBL1783777

SMILES COc1ccc(-c2cc(no2)-c2ccccc2)c(OCCN2CCCCC2)c1

InChI Key InChIKey=MFPWLXKLEDRKJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346153   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50346153(5-(4-methoxy-2-(2-(piperidin-1-yl)ethoxy)phenyl)-3...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50346153(5-(4-methoxy-2-(2-(piperidin-1-yl)ethoxy)phenyl)-3...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed